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α-Vitamin E (Standard) is the analytical standard of α-Vitamin E. This product is intended for research and analytical applications. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant.
Analytical standard grade
Reference standard supplied assay
Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Potent antioxidant
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Abiraterone acetate (CAS 154229-18-2) is the 3 -acetate ester prodrug of abiraterone a steroidal inhibitor of androgen biosynthesis Abiraterone selectively and irreversibly inhibits cytochrome P450 17 -hydroxylase/17 20-lyase (CYP17) an enzyme critical for the synthesis of androgen and cortisol This inhibition occurs via covalent binding and is characterized by a reported IC50 of 72 nM Abiraterone s potency attributed to its 3-pyridyl substituent exceeds that of ketoconazole by 10- to 30-fold in CYP17 inhibition Abiraterone acetate is widely used in research exploring mechanisms and interventions for castration-resistant prostate cancer
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8-Epidiosbulbin E acetate (CAS No 91095-48-6) is a naturally occurring compound derived from plants in the Dioscoreaceae family often studied within the pharmacological research category due to its bioactive properties The mechanism of action involves modulation of cellular pathways including apoptosis-inducing and anti-inflammatory effects It exhibits in vitro activity in the nanomolar to low micromolar range targeting cancer cell lines and showing potential in inhibiting tumor growth Typical applications include evaluations in cell models to assess cytotoxic effects animal studies to explore therapeutic implications and drug screening for anticancer properties Experimental concentrations typically depend on the specific research design ensuring accurate assessment of efficacy and safety in various biological systems
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Resomelagon acetate (AP1189 acetate) is a potent, orally active melanocortin receptor (MR) agonist, specifically targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, exhibiting anti-inflammatory activity. This compound is applicable for research in obesity and chronic inflammation.
Potent, orally active melanocortin receptor agonist
Specifically targets MC1 and MC3
Induces ERK1/2 phosphorylation and Ca2+ mobilization
Exhibits anti-inflammatory activity
Inhibits TNF-α release and efferocytosis
Promotes resolution of acute inflammation
Reduces arthritis in mice
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RI-AG03 acetate is the acetate of RI-AG03. It is an orally active and BBB-penetrable Tau aggregation peptide inhibitor. It inhibits Tau aggregation and improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models, making it suitable for studying tauopathies such as Alzheimer's disease.
Orally active and BBB-penetrable Tau aggregation peptide inhibitor
Inhibits Tau aggregation
Improves associated neurodegeneration and behavioral phenotypes in both in vivo and in vitro models
Suitable for studying tauopathies such as Alzheimer's disease
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